Berikut hasil lengkap Liga Inggris pekan ke-38:
Manchester City 3 - 2 Aston Villa
Liverpool 3 - 1 Wolves
Chelsea 2 - 1 Watford
Norwich City 0 - 5 Tottenham
Arsenal 5 - 1 Everton
Crystal Palace 1 - 0 Manchester United
Brighton 3 - 1 West Ham
Leicester City 4 - 1 Southampton
Burnley 1 - 2 Newcastle
Brentford 1 - 2 Leeds United
Berikut klasemen akhir Liga Inggris 2021/22:
| No | Klub | Selisih Gol | Poin |
| 1 | Manchester City (Juara Liga dan lolos Liga Champions) | 73 | 93 |
| 2 | Liverpool (Lolos Liga Champions) | 68 | 92 |
| 3 | Chelsea (Lolos Liga Champions) | 43 | 74 |
| 4 | Tottenham Hotspur (Lolos Liga Champions) | 29 | 71 |
| 5 | Arsenal (Lolos Liga Europa) | 13 | 69 |
| 6 | Manchester United (Lolos Liga Europa) | 0 | 58 |
| 7 | West Ham United (Lolos Liga Conference) | 9 | 56 |
| 8 | Leicester City | 3 | 52 |
| 9 | Brighton & Hove Albion | -2 | 51 |
| 10 | Wolves | -5 | 51 |
| 11 | Newcastle United | -18 | 49 |
| 12 | Crystal Palace | 4 | 48 |
| 13 | Brentford | -8 | 46 |
| 14 | Aston Villa | -2 | 45 |
| 15 | Southampton | -24 | 40 |
| 16 | Everton | -23 | 39 |
| 17 | Leeds United | -37 | 38 |
| 18 | Burnley (Degradasi) | -19 | 35 |
| 19 | Watford (Degradasi) | -43 | 23 |
| 20 | Norwich City (Degradasi) | -61 | 22 |
